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Troponin bound to heparin causes decreased calculated troponin plasma concentration in comparison to serum.[76] Other resources of interference that could have an impact on the assay detection course of action and cause Phony-destructive troponin values involve ascorbic acid in immunoenzymometric assays applying alkaline phosphatase, biotin in assays utilizing a biotinylated antibody, streptokinase within the presence of streptavidin, and large titers of antibodies to ruthenium or streptavidin in cTnT assays.

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Besides Untrue-beneficial results, heterophile antibodies can result in falsely low benefits when they bind towards the topanwin login variable locations from the capture antibody, mimicking the antigen to become calculated and blocking troponin from binding.[89] The mostly used procedure for minimizing the effect of HAMA on professional immunoassays will be the addition of non-immune mouse immunoglobulin (IgG).

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